Jump to content

Coronavirus (COVID-19)

Webmaster

By Webmaster
in This aint sports talk!

 Share

Recommended Posts

K9

K9

Posted
Posted
9 minutes ago, bucsfan333 said:

I mean. Hospitals are full of germs. It's gotta be tenfold compared to your own home simply due to the traffic and the fact that sick people flood hospitals.

But the people that work at hospitals know what they're doing. They do it every day. And they're really good at it. So it's doubtful you'll die or have complications.

So...

It seems from the limited info I heard, they were encouraging the moms-to-be to still have the baby at the hospital. The stress that it puts on the midwife (if they have one) and the mom was more dangerous than having at the hospital...  ??  But it could be just this area, since at the time - they had the capacity for them.  It might not be the same for other areas like those they are considering the epicenters.

Link to comment
Share on other sites
naptownskinsfan

naptownskinsfan

Posted
Posted
1 hour ago, bucsfan333 said:

It's sad, but you've gotta worry about baby snatchers. Every baby gets an ankle monitor that will go off at the door.

That, and having their own clean floor separate from the rest of the sick people is just a good idea.

I had a buddy of mine who had two stints at Johns Hopkins for a heart condition in Baltimore.  What sucks is that they converted all of their vending machines and cafeteria to all diet drinks, but we found out the maternity floor had machines with regular sodas in them so if we needed something, one of us would raid the maternity floor machine.  We weren't the only ones who knew that, either.  

Link to comment
Share on other sites
N4L

N4L

Posted
Posted
On 3/26/2020 at 11:53 AM, Shanedorf said:

I wrote a little more info here, hope it helps

An antibody is a complex protein molecule produced by B cells in response to invaders, an amazing system honed by millions of years of evolution.

The five subclasses of antibodies are:

  1. Immunoglobulin A (IgA), which is found in high concentrations in the mucous membranes, particularly those lining the respiratory passages and gastrointestinal tract, as well as in saliva and tears.
  2. Immunoglobulin G (IgG), the most abundant type of antibody, is found in all body fluids and protects against bacterial and viral infections.
  3. Immunoglobulin M (IgM), which is found mainly in the blood and lymph fluid, is the first antibody to be made by the body to fight a new infection.
     
  4. Immunoglobulin E (IgE), which is associated mainly with allergic reactions (when the immune system overreacts to environmental antigens such as pollen or pet dander). It is found in the lungs, skin, and mucous membranes.
  5. Immunoglobulin D (IgD), which exists in small amounts in the blood, is the least understood antibody.

The first- responders in a respiratory infection are the secretory IgA antibodies, but there are questions about how efficient they are in forming memory cells that lead to lasting immunity. The IgG and IgM antibodies are found in your bloodstream and are the likely source of the new tests linked earlier.

The IgM antibody is less specific, but more prolific -  so early on it plays a bigger role in knocking down the infections.Then the IgG takes over and is more specific to the exact viral intruder and forms lasting immunity -  so you're ready next time around. (Vaccines typically lean on IgG production)

All of this takes some time from initial insult until your body builds up the immunity, so you're looking at about 3 weeks post-infection to have useful amounts of these anti-virus antibodies. Once these antibodies bind to the intruder, it initiates a cascade of events that lead to killing of the virus
In many ways, these antibodies are tagging the virus so the killing cells can take em out (without killing you at the same time )

The current test kits which are in short supply look for the presence of viral RNA and indicate if you have virus in you right now. An antibody test only shows that you were exposed to the virus at some point, but offer little insight into your current viral load. 

https://www.biospace.com/article/vir-biotechnology-ids-2-monoclonal-antibodies-against-the-covid-19-coronavirus/

Quote

 

San Francisco-based Vir Biotechnology indicated it has identified several human monoclonal antibody (mAb) candidates against SARS-CoV-2, the virus causing COVID-19. In the interest of saving time, the company’s lead development was transferred to WuXi Biologics and Biogen several weeks ago with human trials likely to begin in the next three to five months.

The lead antibody’s ability to neutralize the SARS-CoV-2 live virus has been confirmed in two different laboratories. It binds to an epitope—the specific part of an antigen molecule on the virus—on SARS-CoV-2 that is also seen on the SARS-CoV-1 virus that causes SARS. This means the antigen is highly conserved and less likely to disappear should the viruses mutate or develop resistance to the antibody.

 

This really should be called SARS-2. Its very very similar to SARS-1. This company has identified an antibody that tags the virus of SARS-1 so that other cells come to kill them and realized it works for SARS-2 as well. That gives them a gigantic head start on developing a treatment / vaccine. I have been told that you cannot make the vaccine without first making the necessary antibodies to imprint it, so to speak. So this is step 1. 

All of these other malaria Ebola drugs are a pipe dream. Tweaked versions or drug cocktails containing those drugs are not / were never the answer. The answer is SARS / MERS drugs. 

3-5 months before human trials. That is very fast. this would be huge. 

 

One thing that is so invigorating about this pandemic is that we have the totality of our collective brainpower focused soley on collectively crushing SARS-2. thats pretty cool. 

  • Like 2
Link to comment
Share on other sites
BayRaider

BayRaider

Posted
Posted

https://www.worldometers.info/coronavirus/

17% Death Rate in Closed Cases now like several people predicted. Original Sars started at 6-7% like this one, went up to 17-18% and settled around 14%. 
 

People highly exaggerate the amount of non official mild cases that would make death rate go down. The death was never anywhere close to 3%. Maybe 8-10%. Almost everyone who has mild symptoms is getting checked out of paranoia. 

Link to comment
Share on other sites
malagabears

malagabears

Posted
Posted

Howdi all, Spanish Bears fan. Here in Spain de have been hit exceptionally hard in Madrid & Barcelona. My region of Andalucía has been spared but we still have 4277 cases. Keep safe everyone.

We have been under a strict curfew for 2 weeks and have 2 more to go. Hopefully there is now light at the end of the tunnel. They are forecasting our curve to flatten in the next few days.

  • Like 1
Link to comment
Share on other sites
mistakey

mistakey

Posted
Posted
16 minutes ago, BayRaider said:

https://www.worldometers.info/coronavirus/

17% Death Rate in Closed Cases now like several people predicted. Original Sars started at 6-7% like this one, went up to 17-18% and settled around 14%. 
 

People highly exaggerate the amount of non official mild cases that would make death rate go down. The death was never anywhere close to 3%. Maybe 8-10%. Almost everyone who has mild symptoms is getting checked out of paranoia. 

Yeah pretty sure you still cant get a test in a lot of the country

Link to comment
Share on other sites
BayRaider

BayRaider

Posted
Posted
11 minutes ago, mistakey said:

Yeah pretty sure you still cant get a test in a lot of the country

Yes but that death rate is no where near 3%, unofficial cases or not. SARS de ja vu, man. 2-3% blah blah blah. Ended up being projected at 15% a decade later, with the projected unofficial cases. 

Link to comment
Share on other sites
aussie_eagle

aussie_eagle

Posted
Posted

in Australia (where I live) they were only testing people from overseas or who had a confirmed contact with a positive tested person. Now they have changed this to basically all people I believe I think cases will increase. Australia has done very well so far though, all deaths are people aged 75+ I believe. Most people are taking social distancing seriously here.

  • Like 1
Link to comment
Share on other sites
BayRaider

BayRaider

Posted
Posted

Another thing to consider is the “Mild Condition” rate has stayed consistent at 94% the entire breakout while the death rate has climbed to 17% worldwide. This kills you out of no where in your house if you are one of the younger deaths. 

Link to comment
Share on other sites
naptownskinsfan

naptownskinsfan

Posted
Posted
4 hours ago, N4L said:

https://www.biospace.com/article/vir-biotechnology-ids-2-monoclonal-antibodies-against-the-covid-19-coronavirus/

This really should be called SARS-2. Its very very similar to SARS-1. This company has identified an antibody that tags the virus of SARS-1 so that other cells come to kill them and realized it works for SARS-2 as well. That gives them a gigantic head start on developing a treatment / vaccine. I have been told that you cannot make the vaccine without first making the necessary antibodies to imprint it, so to speak. So this is step 1. 

All of these other malaria Ebola drugs are a pipe dream. Tweaked versions or drug cocktails containing those drugs are not / were never the answer. The answer is SARS / MERS drugs. 

3-5 months before human trials. That is very fast. this would be huge. 

 

One thing that is so invigorating about this pandemic is that we have the totality of our collective brainpower focused soley on collectively crushing SARS-2. thats pretty cool. 

That's awesome news.  It would still be 14-18 months after human trials are started that we would see a vaccine from this though, correct? 

Link to comment
Share on other sites
Guest
This topic is now closed to further replies.
 Share
Go to topic listing


×
×
  • Create New...