Jump to content

Coronavirus (COVID-19)


Webmaster

Recommended Posts

A man in Hong Kong has become the first confirmed patient to be infected with the coronavirus a second time, according to researchers at the University of Hong Kong.

https://www.nbcnews.com/science/science-news/hong-kong-man-was-reinfected-coronavirus-researchers-say-n1237840?cid=sm_npd_ms_fb_ma&fbclid=IwAR0wpw1QbrC6Yn8ReV-cKBuviVZWJ5LiQ2ZSJ8CPGl3X8RW89KY8qaH9xxA

Link to comment
Share on other sites

I have been tracking this religiously because I know it's coming. 

https://www.wxyz.com/news/woman-pronounced-dead-later-found-to-be-still-breathing-at-detroit-funeral-home

First it was a corpse moving as the coffin was being lowered, now a person pronounced dead was breathing.  At this pace it's only weeks before zombies. 

Get your canned chicken, get your tuna, gt your brown rice and stock up on ammunition the zombie apocalypse is next. 

THIS is why everyone is preaching wearing a mask.  They want everyone to have one on when they die so it's harder for the zombies to bite them.  They've known all along.  They don't care about saving lives now, they just want a bunch of masked zombies so the zombies are less of a threat.

You're already zombies if you can't put two and two together. 

Link to comment
Share on other sites

24 minutes ago, TVScout said:

A man in Hong Kong has become the first confirmed patient to be infected with the coronavirus a second time, according to researchers at the University of Hong Kong.

https://www.nbcnews.com/science/science-news/hong-kong-man-was-reinfected-coronavirus-researchers-say-n1237840?cid=sm_npd_ms_fb_ma&fbclid=IwAR0wpw1QbrC6Yn8ReV-cKBuviVZWJ5LiQ2ZSJ8CPGl3X8RW89KY8qaH9xxA

eNegu58.gif

  • Like 1
Link to comment
Share on other sites

https://www.eurekalert.org/pub_releases/2020-08/uoea-bpm082020.php

"Blood pressure medication improves COVID-19 survival rates"

Copied from Reddit:

Link to the meta-analysis:

https://link.springer.com/article/10.1007/s11883-020-00880-6

Of note, this is a meta-analysis of observational studies. These studies were retrospective, and no change/treatment was given. They're just looking at what medications the people are prescribed normally and seeing how they're doing.

In ~a week we will have the first large scale randomized control trial results relating to ACE inhibitors and ARBs in COVID-19 (BRACE CORONA). The BRACE trial is kinda weird - they are having hypertensive patients either 1. stop their ACEi/ARB and switch to a new blood pressure medication 2. continue taking their ACEi/ARB.

Soon we will have larger, *treatment* trials of these drugs. There is preliminary data from a randomized control trial of telmisartan (an ARB) from Argentina that was released last week. It showed potentially strong benefit:

https://www.medrxiv.org/content/10.1101/2020.08.04.20167205v2

Note that this Argentina trial was in people who don't have high blood pressure - it was a trial to see if the drug helped with COVID-19. So far it looks like it might.

If these drugs help with COVID-19 it would be really, really, really good. Because they're ubiquitous, insanely safe, cheap and every doctor on earth knows about them and is comfortable prescribing them.

Link to comment
Share on other sites

Just now, BobbyPhil1781 said:

That sucks if you have to wait that long. What symptoms do you have if you don't mind divulging that info?

Current symptoms: shortness of breath, cough, night sweats, diarrhea, fatigue, large pp, dehydration, disorientation, body aches

Link to comment
Share on other sites

56 minutes ago, TVScout said:

Not free unfortunately:

China says it began public use of covid-19 vaccine a month ago, bypassing clinical trials

https://www.washingtonpost.com/world/asia_pacific/china-coronavirus-vaccine-bypass-clinical-trials/2020/08/24/1813779a-e5be-11ea-bf44-0d31c85838a5_story.html

Of course there are issues with a vaccine that skipped clinical trials.

  • Like 3
Link to comment
Share on other sites

42 minutes ago, Tyty said:

Current symptoms: shortness of breath, cough, night sweats, diarrhea, fatigue, large pp, dehydration, disorientation, body aches

Well hopefully you get over it soon and don't have to spend money getting new pants since when everything gets back to normal, you might not need em.

  • Like 1
Link to comment
Share on other sites

1 hour ago, vikesfan89 said:
2 hours ago, TVScout said:

 

Is this guy just upset that it was called big news or that it's been approved?

 

Or is it all about who announced it?

Probably a little bit of both tbh.

The "news" yesterday wasn't really news, and there should be legitimate outrage at the President publicly lobbying the FDA for drug approvals. Especially when combined with his obvious financial conflicts of interest.

But most of his questions are comparing this to a traditional small molecule drug, and range in applicability from "we should learn about this with more focused trials" to "you're just being pedantic". Like, really, receiving a plasma donation isn't safe now? What, we need a traditional animal study where we find out how much plasma donated they can handle? I can't even really respond to that without sarcasm. 

  • Like 2
Link to comment
Share on other sites

6 minutes ago, ramssuperbowl99 said:

The "news" yesterday wasn't really news,

here's the statement:

"The emergency use authorization means that the convalescent plasma "may" be effective in treating COVID-19 and that the known and potential benefits of the product outweigh the known and potential risks,"
 

translation: we don't yet have full efficacy data and we don't yet know which patients ( age, co-morbidity, disease state etc) it works best for, but we've used convalescent plasma for 100 years and the safety risk appears minimal, so let's give it a try while we learn more.
 

Is it just Fanfare for the Common Man ? Sure, why not

 

 

  • Like 2
Link to comment
Share on other sites

One challenge with an airborne respiratory disease is that the first interaction with humans is through the airway. And that means IgA- a specialized antibody system that lines the airway is the first to react...and I'm not aware of any work in convalescent mucous yet. 
So by the time the virus reaches the bloodstream (where convalescent plasma helps) you've already got an infection happening. It may buy these patients critical time to recover and I'm sure the MDs are happy to have another arrow in their quiver.

However, plasma has a limited lifespan (about 30 days) which means you can't store it forever and you have to transport it from the collection site to where the patients are - so it doesn't scale very well like a drug or vaccine would.

  • Like 2
Link to comment
Share on other sites

Guest
This topic is now closed to further replies.
×
×
  • Create New...